Please use this identifier to cite or link to this item:
https://hdl.handle.net/10216/103987
Full metadata record
DC Field | Value | Language |
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dc.creator | I. B. Gomes | |
dc.creator | J. Malheiro | |
dc.creator | F. Mergulhão | |
dc.creator | J.Y. Maillard | |
dc.creator | M. Simões | |
dc.date.accessioned | 2022-09-11T01:41:52Z | - |
dc.date.available | 2022-09-11T01:41:52Z | - |
dc.date.issued | 2016 | |
dc.identifier.issn | 2049-632X | |
dc.identifier.other | sigarra:144213 | |
dc.identifier.uri | https://hdl.handle.net/10216/103987 | - |
dc.description.abstract | New biocidal solutions are needed to combat effectively the evolution of microbes developing antibiotic resistance while having a low or no environmental toxicity impact. This work aims to assess the efficacy of commonly used biocides and natural-based compounds on the disinfection of silicone and stainless steel (SS) surfaces seeded with different Staphylococcus aureus strains. Minimum inhibitory concentration was determined for synthetic (benzalkonium chloride-BAC, glutaraldehyde-GTA, ortho-phthalaldehyde-OPA and peracetic acid-PAA) and natural-based (cuminaldehyde-CUM), eugenol-EUG and indole-3-carbinol-I3C) biocides by the microdilution method. The efficacy of selected biocides at MIC, 10 x MIC and 5500 mg/L (representative in-use concentration) on the disinfection of sessile S. aureus on silicone and SS was assessed by viable counting. Silicone surfaces were harder to disinfect than SS. GTA, OPA and PAA yielded complete CFU reduction of sessile cells for all test concentrations as well as BAC at 10 x MIC and 5500 mg/L. CUM was the least efficient compound. EUG was efficient for SS disinfection, regardless of strains and concentrations tested. I3C at 10 x MIC and 5500 mg/L was able to cause total CFU reduction of silicone and SS deposited bacteria. Although not so efficient as synthetic compounds, the natural-based biocides are promising to be used in disinfectant formulations, particularly I3C and EUG. | |
dc.language.iso | eng | |
dc.relation | info:eu-repo/grantAgreement/FCT - Fundação para a Ciência e a Tecnologia/Projetos Estratégicos/UID/EQU/00511/2013 - POCI-01-0145-FEDER-006939/Laboratório de Engenharia de Processos, Ambiente, Biotecnologia e Energia/LEPABE | |
dc.relation | info:eu-repo/grantAgreement/Autoridade de Gestão do Programa Operacional Regional do Norte/Programas Integrados de IC&DT/NORTE-07-0124-FEDER-000025/(Bio) Chemical Engineering: Multi-Scale Approaches for Sustainable Environment and Health/LEPAE/CEFT - RL2 | |
dc.relation | info:eu-repo/grantAgreement/FCT - Fundação para a Ciência e a Tecnologia/Projectos de I&DT em Todos os Domínios Científicos/PTDC/DTP-SAP/1078/2012|FCOMP-01-0124-FEDER-028765/Desinfeção de bactérias planctónicas e biofilmes em ambientes hospitalares com produtos fitoquímicos/Fitodesinfetantes | |
dc.rights | restrictedAccess | |
dc.title | Comparison of the efficacy of natural-based and synthetic biocides to disinfect silicone and stainless steel surfaces | |
dc.type | Artigo em Revista Científica Internacional | |
dc.contributor.uporto | Faculdade de Engenharia | |
dc.identifier.doi | 10.1093/femspd/ftw014 | |
dc.identifier.authenticus | P-00K-THT | |
Appears in Collections: | FEUP - Artigo em Revista Científica Internacional |
Files in This Item:
File | Description | Size | Format | |
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144213.1.pdf | Post-Print version | 591.1 kB | Adobe PDF | View/Open |
144213.pdf Restricted Access | Artigo original publicado | 526.49 kB | Adobe PDF | Request a copy from the Author(s) |
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