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Author(s): J. M. R. Moreira
J. D. P. Araújo
J. M. Miranda
M. Simões
L. F. Melo
F. J. Mergulhão
Title: The effects of surface properties on escherichia coli adhesion are modulated by shear stress
Issue Date: 2014
Abstract: The adhesion of Escherichia colito glass and polydimethylsiloxane (PDMS) at different flow rates (between1 and 10 ml s−1) was monitored in a parallel plate flow chamber in order to understand the effect of surface properties and hydrodynamic conditions on adhesion. Computational fluid dynamics was used toassess the applicability of this flow chamber in the simulation of the hydrodynamics of relevant biomedical systems. Wall shear stresses between 0.005 and 0.07 Pa were obtained and these are similar to thosefound in the circulatory, reproductive and urinary systems. Results demonstrate that E. coli adhesion tohydrophobic PDMS and hydrophilic glass surfaces is modulated by shear stress with surface propertieshaving a stronger effect at the lower and highest flow rates tested and with negligible effects at intermediate flow rates. These findings suggestthat when expensive materials or coatings are selected to producebiomedical devices, this choice should take into account the physiological hydrodynamic conditions thatwill occur during the utilization of those devices.
Subject: Ciências Tecnológicas, Ciências da engenharia e tecnologias
Technological sciences, Engineering and technology
Scientific areas: Ciências da engenharia e tecnologias
Engineering and technology
Related Information: info:eu-repo/grantAgreement/FCT - Fundação para a Ciência e Tecnologia/Projectos de I&DT em Todos os Domínios Científicos/PTDC/EBB-BIO/104940/2008/Estudo das condições iniciais que controlam a formação de biofilmes/Filmstart
info:eu-repo/grantAgreement/FCT - Fundação para a Ciência e Tecnologia/Projectos de I&DT em Todos os Domínios Científicos/PTDC/EQU-FTT/105535/2008/Sujamento e limpeza de micro canais/PTDC/EQU-FTT/105535/2008
Document Type: Artigo em Revista Científica Internacional
Rights: restrictedAccess
Appears in Collections:FEUP - Artigo em Revista Científica Internacional

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