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dc.creatorJ. M. R. Moreira
dc.creatorJ. S. Teodósio
dc.creatorF. C. Silva
dc.creatorM. Simões
dc.creatorL. F. Melo
dc.creatorF. J. Mergulhão
dc.description.abstractThis work investigates the effect of flow rate variation on mass transfer and on the development of Escherichia coli biofilms on a flow cell reactor under turbulent flow conditions. Computational fluid dynamics (CFD) was used to assess the applicability of this reactor for the simulation of industrial and biomedical biofilms and the numerical results were validated by streak photography. Two flow rates of 374 and 242 L h(-1) (corresponding to Reynolds numbers of 6,720 and 4,350) were tested and wall shear stresses between 0.183 and 0.511 Pa were predicted in the flow cell reactor. External mass transfer coefficients of 1.38 x 10(-5) and 9.64 x 10(-6) m s(-1) were obtained for the higher and lower flow rates, respectively. Biofilm formation was favored at the lowest flow rate because shear stress effects were more important than mass transfer limitations. This flow cell reactor generates wall shear stresses that are similar to those found in some industrial and biomedical settings, thus it is likely that the results obtained on this work can be used in the development of biofilm control strategies in both scenarios.
dc.relationinfo:eu-repo/grantAgreement/FCT - Fundação para a Ciência e Tecnologia/Programa MIT-Portugal/MIT-Pt/BS-BB/0082/2008/Biologia de sistemas e Biologia sintética no desenvolvimento de fábricas celulares microbianas melhoradas/MIT-Pt/BS-BB/0082/2008
dc.relationinfo:eu-repo/grantAgreement/FCT - Fundação para a Ciência e Tecnologia/Projectos de I&DT em Todos os Domínios Científicos/PTDC/EBB-BIO/104940/2008/Estudo das condições iniciais que controlam a formação de biofilmes/Filmstart
dc.subjectBiotecnologia, Engenharia química
dc.subjectBiotecnology, Chemical engineering
dc.titleInfluence of flow rate variation on the development of Escherichia coli biofilms
dc.typeArtigo em Revista Científica Internacional
dc.contributor.uportoFaculdade de Engenharia
dc.subject.fosCiências da engenharia e tecnologias::Engenharia química
dc.subject.fosEngineering and technology::Chemical engineering
Appears in Collections:FEUP - Artigo em Revista Científica Internacional

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