A model for cancer chemotherapy with state-space constraints

Please use this identifier to cite or link to this item: https://hdl.handle.net/10216/102313

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DC Field	Value	Language
dc.creator	Maria do Rosário de Pinho
dc.creator	Maria Margarida Ferreira
dc.creator	Urszula Ledzewicz
dc.creator	Heinz Schaettler
dc.date.accessioned	2022-09-08T23:30:56Z	-
dc.date.available	2022-09-08T23:30:56Z	-
dc.date.issued	2005
dc.identifier.issn	0362-546X
dc.identifier.other	sigarra:55903
dc.identifier.uri	https://hdl.handle.net/10216/102313	-
dc.description.abstract	The analysis of optimal control problems is significantly more difficult when state space constraints are imposed and thus in many modelling approaches explicit constraints are handled by including penalty terms in the objective. In this paper, we use the example of a simple model for cancer chemotherapy to compare the structure of extremals when upper limits on the total number of cancer cells are imposed (a) implicitly through a penalty term in the objective and (b) explicitly in the form of state-space constraints.
dc.language.iso	eng
dc.rights	restrictedAccess
dc.subject	Engenharia de controlo, Matemática
dc.subject	Control engineering, Mathematics
dc.title	A model for cancer chemotherapy with state-space constraints
dc.type	Artigo em Revista Científica Internacional
dc.contributor.uporto	Faculdade de Engenharia
dc.identifier.doi	10.1016/j.na.2005.02.004
dc.identifier.authenticus	P-000-0E2
dc.subject.fos	Ciências exactas e naturais::Matemática
dc.subject.fos	Natural sciences::Mathematics
Appears in Collections:	FEUP - Artigo em Revista Científica Internacional

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