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dc.creatorMaria do Rosário de Pinho
dc.creatorMaria Margarida Ferreira
dc.creatorUrszula Ledzewicz
dc.creatorHeinz Schaettler
dc.description.abstractThe analysis of optimal control problems is significantly more difficult when state space constraints are imposed and thus in many modelling approaches explicit constraints are handled by including penalty terms in the objective. In this paper, we use the example of a simple model for cancer chemotherapy to compare the structure of extremals when upper limits on the total number of cancer cells are imposed (a) implicitly through a penalty term in the objective and (b) explicitly in the form of state-space constraints.
dc.subjectEngenharia de controlo, Matemática
dc.subjectControl engineering, Mathematics
dc.titleA model for cancer chemotherapy with state-space constraints
dc.typeArtigo em Revista Científica Internacional
dc.contributor.uportoFaculdade de Engenharia
dc.subject.fosCiências exactas e naturais::Matemática
dc.subject.fosNatural sciences::Mathematics
Appears in Collections:FEUP - Artigo em Revista Científica Internacional

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