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dc.creatorLuísa C. Sousa
dc.creatorCatarina F. Castro
dc.creatorCarlos C. António
dc.creatorAndré Miguel F. Santos
dc.creatorRosa Maria dos Santos
dc.creatorPedro Miguel A. C. Castro
dc.creatorElsa Azevedo
dc.creatorJoão Manuel R. S. Tavares
dc.description.abstractThe ability of using non-expensive ultrasound (US) image data together with computer fluid simulation to access various severities of carotid stenosis was inquired in this study. Subject-specific hemodynamic conditions were simulated using a developed finite element solver. Individual structured meshing of the common carotid artery (CCA) bifurcation was built from segmented longitudinal and cross-sectional US images; imposed boundary velocities were based on Doppler US measurements. Simulated hemodynamic parameters such as velocities, wall shear stress (WSS) and derived descriptors were able to predict disturbed flow conditions which play an important role in the development of local atherosclerotic plaques. Hemodynamic features from six individual CCA bifurcations were analyzed. High values of time-averaged WSS (TAWSS) were found at stenosis site. Low values of TAWSS were found at the bulb and at the carotid internal and external branches depending on the particular features of each patient. High oscillating shear index and relative residence time values assigned highly disturbed flows at the same artery surface regions that correlate only moderately with low TAWSS results. Based on clinic US examinations, results provide estimates of flow changes and forces at the carotid artery wall toward the link between hemodynamic behavior and stenosis pathophysiology.
dc.subjectCiências Tecnológicas, Ciências da computação e da informação
dc.subjectTechnological sciences, Computer and information sciences
dc.titleToward hemodynamic diagnosis of carotid artery stenosis based on ultrasound image data and computational modeling
dc.typeArtigo em Revista Científica Internacional
dc.contributor.uportoFaculdade de Medicina
dc.contributor.uportoFaculdade de Engenharia
dc.subject.fosCiências exactas e naturais::Ciências da computação e da informação
dc.subject.fosNatural sciences::Computer and information sciences
Appears in Collections:FEUP - Artigo em Revista Científica Internacional
FMUP - Artigo em Revista Científica Internacional

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