Please use this identifier to cite or link to this item:
https://hdl.handle.net/10216/92804
Author(s): | Araujo, JR ramalho, c Correia Branco, A Faria, A Ferraz, T Keating, E Martel, F |
Title: | A parallel increase in placental oxidative stress and antioxidant defenses occurs in pre-gestational type 1 but not gestational diabetes |
Issue Date: | 2013 |
Abstract: | We aimed to determine the oxidative stress status in placentas obtained from gestational (GDM) and type 1 (T1D) diabetic pregnancies. Malonaldehyde and protein carbonyls, two biomarkers of oxidative damage, were higher in T1D but not in GDM placentas. Also, higher reduced glutathione and lower oxidized glutathione levels and higher glutathione peroxidase activity were found in T1D but not in GDM placentas. These results suggest that T1D placentas may develop a protective antioxidant mechanism to overcome higher oxidative stress levels. |
Subject: | Ciências da Saúde Health sciences |
URI: | https://hdl.handle.net/10216/92804 |
Document Type: | Artigo em Revista Científica Internacional |
Rights: | restrictedAccess |
Appears in Collections: | FCUP - Artigo em Revista Científica Internacional FMUP - Artigo em Revista Científica Internacional |
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47887.pdf Restricted Access | 473.66 kB | Adobe PDF | Request a copy from the Author(s) |
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