Please use this identifier to cite or link to this item: https://hdl.handle.net/10216/76146
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dc.creatorVítor Amálio Maia Martins Moreira
dc.date.accessioned2022-09-11T21:57:54Z-
dc.date.available2022-09-11T21:57:54Z-
dc.date.issued2014-07-11
dc.date.submitted2014-08-06
dc.identifier.othersigarra:31600
dc.identifier.urihttps://hdl.handle.net/10216/76146-
dc.descriptionThe emergence of high-throughput sequencing has brought substantial advances in cancer genomics research. The current pace of advance of this technology made possible to assay with high depth of coverage the DNA and the transcriptomes (RNA-seq) of tumor samples and cancer cell lines. Aberrant RNA processing of genes plays an important role in cancer. The goal of this project is to develop a computational platform that enables the use of powerful computational resources for studies involving the analysis of high-throughput information from the transcriptome of cancer samples. The platform hides the computational resources from the user making it easy to use by the Life Sciences experts. Although the platform is general purpose, the current version is tuned for to the application of methods that use high-throughput information from the transcriptome of cancer samples to identify events of aberrant splicing and their impact in the transcript structure.
dc.language.isoeng
dc.rightsopenAccess
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/
dc.subjectCiências da computação e da informação
dc.subjectComputer and information sciences
dc.titleA Computational Platform for Assessing the Impact of Alternative Splicing in Cancer
dc.typeDissertação
dc.contributor.uportoFaculdade de Engenharia
dc.identifier.tid201322862
dc.subject.fosCiências exactas e naturais::Ciências da computação e da informação
dc.subject.fosNatural sciences::Computer and information sciences
thesis.degree.disciplineMestrado Integrado em Engenharia Informática e Computação
thesis.degree.grantorFaculdade de Engenharia
thesis.degree.grantorUniversidade do Porto
thesis.degree.level1
Appears in Collections:FEUP - Dissertação

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