Utilize este identificador para referenciar este registo:
https://hdl.handle.net/10216/120514
Autor(es): | Ribeiro C. Santos C. Gonçalves V. Ramos A. Afonso C. Tiritan M.E. |
Título: | Chiral drug analysis in forensic chemistry: An overview |
Editor: | MDPI |
Data de publicação: | 2018 |
Resumo: | Many substances of forensic interest are chiral and available either as racemates or pure enantiomers. Application of chiral analysis in biological samples can be useful for the determination of legal or illicit drugs consumption or interpretation of unexpected toxicological effects. Chiral substances can also be found in environmental samples and revealed to be useful for determination of community drug usage (sewage epidemiology), identification of illicit drug manufacturing locations, illegal discharge of sewage and in environmental risk assessment. Thus, the purpose of this paper is to provide an overview of the application of chiral analysis in biological and environmental samples and their relevance in the forensic field. Most frequently analytical methods used to quantify the enantiomers are liquid and gas chromatography using both indirect, with enantiomerically pure derivatizing reagents, and direct methods recurring to chiral stationary phases. © 2018 by the authors. |
Assunto: | drug devices forensic science gas chromatography liquid chromatography procedures Chromatography, Gas Chromatography, Liquid Forensic Sciences Pharmaceutical Preparations |
URI: | https://hdl.handle.net/10216/120514 |
Fonte: | Molecules, vol. 23(2):262 |
Informação Relacionada: | info:eu-repo/grantAgreement/FCT/5876/147268/PT |
Tipo de Documento: | Artigo em Revista Científica Internacional |
Condições de Acesso: | openAccess |
Aparece nas coleções: | CIIMAR - Artigo em Revista Científica Internacional |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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Ribeiro C_2018.pdf | 13.17 MB | Adobe PDF | Ver/Abrir |
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