Please use this identifier to cite or link to this item:
https://hdl.handle.net/10216/120412
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.creator | Pinheiro C. | |
dc.creator | Azevedo J. | |
dc.creator | Campos A. | |
dc.creator | Vasconcelos V. | |
dc.creator | Loureiro S. | |
dc.date.accessioned | 2019-05-31T16:15:31Z | - |
dc.date.available | 2019-05-31T16:15:31Z | - |
dc.date.issued | 2016 | |
dc.identifier.issn | 15733017, 09639292 | |
dc.identifier.uri | https://hdl.handle.net/10216/120412 | - |
dc.description.abstract | Microcystin-LR (MC-LR) and cylindrospermopsin (CYN) are the most representative cyanobacterial cyanotoxins. They have been simultaneously detected in aquatic systems, but their combined ecotoxicological effects to aquatic organisms, especially microalgae, is unknown. In this study, we examined the effects of these cyanotoxins individually and as a binary mixture on the growth rate of the freshwater algae Chlorella vulgaris. Using the MIXTOX tool, the reference model concentration addition (CA) was selected to evaluate the combined effects of MC-LR and CYN on the growth of the freshwater green algae due to its conservative prediction of mixture effect for putative similar or dissimilar acting chemicals. Deviations from the CA model such as synergism/antagonism, dose-ratio and dose-level dependency were also assessed. In single exposures, our results demonstrated that MC-LR and CYN had different impacts on the growth rates of C. vulgaris at the highest tested concentrations, being CYN the most toxic. In the mixture exposure trial, MC-LR and CYN showed a synergistic deviation from the conceptual model CA as the best descriptive model. MC-LR individually was not toxic even at high concentrations (37 mg L−1); however, the presence of MC-LR at much lower concentrations (0.4–16.7 mg L−1) increased the CYN toxicity. From these results, the combined exposure of MC-LR and CYN should be considered for risk assessment of mixtures as the toxicity may be underestimated when looking only at the single cyanotoxins and not their combination. This study also represents an important step to understand the interactions among MC-LR and CYN detected previously in aquatic systems. © 2016, Springer Science+Business Media New York. | |
dc.description.sponsorship | This work was supported by the Portuguese Science Foundation (FCT) through CESAM: UID/AMB/50017/2013. | |
dc.language.iso | eng | |
dc.publisher | Springer International Publishing | |
dc.relation.ispartof | Ecotoxicology, vol. 25(4), p. 745-758 | |
dc.rights | restrictedAccess | |
dc.subject | cylindrospermopsin | |
dc.subject | microcystin LR | |
dc.subject | concentration (composition) | |
dc.subject | ecotoxicology | |
dc.subject | enzyme | |
dc.subject | green alga | |
dc.subject | growth rate | |
dc.subject | synergism | |
dc.subject | toxicity | |
dc.subject | toxin | |
dc.subject | analysis of variance | |
dc.subject | Article | |
dc.subject | bacterial growth | |
dc.subject | bacterial strain | |
dc.subject | bacterium culture | |
dc.subject | chemical analysis | |
dc.subject | Chlorella vulgaris | |
dc.subject | concentration response | |
dc.subject | conceptual framework | |
dc.subject | controlled study | |
dc.subject | growth rate | |
dc.subject | high performance liquid chromatography | |
dc.subject | microscopy | |
dc.subject | molecular dynamics | |
dc.subject | nonhuman | |
dc.subject | optical density | |
dc.subject | plant growth | |
dc.subject | prediction | |
dc.subject | priority journal | |
dc.subject | risk assessment | |
dc.subject | algae | |
dc.subject | Chlorella vulgaris | |
dc.subject | Chlorophyta | |
dc.subject | Cyanobacteria | |
dc.title | The interactive effects of microcystin-LR and cylindrospermopsin on the growth rate of the freshwater algae Chlorella vulgaris | |
dc.type | Artigo em Revista Científica Internacional | |
dc.contributor.uporto | CIIMAR - Centro Interdisciplinar de Investigação Marinha e Ambiental | |
dc.identifier.doi | 10.1007/s10646-016-1633-y | |
dc.relation.publisherversion | http://dx.doi.org/10.1007/s10646-016-1633-y | |
Appears in Collections: | CIIMAR - Artigo em Revista Científica Internacional |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Pinheiro C_2016.pdf Restricted Access | 746.14 kB | Adobe PDF | Request a copy |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.