Please use this identifier to cite or link to this item:
https://hdl.handle.net/10216/119294
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.creator | Gomes, J | |
dc.creator | Santos, JD | |
dc.creator | Mauricio, AC | |
dc.date.accessioned | 2019-03-16T00:14:04Z | - |
dc.date.available | 2019-03-16T00:14:04Z | - |
dc.date.issued | 2017 | |
dc.identifier.other | sigarra:275520 | |
dc.identifier.uri | https://hdl.handle.net/10216/119294 | - |
dc.description.abstract | Damage to peripheral nerve fibers results in axonal loss and demyelination followed by regeneration and remyelination under optimal conditions with the possibility of some functional recovery. The experimental challenge is to accelerate axonal regeneration to promote reinnervation and improve functional recovery after peripheral nerve injury. In the past few decades, different types of biological or artificial guide tubes have been developed to bridge the gap of a sectioned nerve, to limit the fibrosis process and to orient the regenerating fibers towards the distal stump. Chitosan is widely used for biomedical applications, including crosslinked with other materials. In this work, chitosan guide tubes were produced and implanted using the rat sciatic nerve animal model. Functional tests were performed as well as a mechanical and structural characterization of the guide tubes. (c) 2017 IEEE. | |
dc.language.iso | eng | |
dc.relation.ispartof | 2017 IEEE 5th Portuguese Meeting on Bioengineering (ENBENG) | |
dc.rights | openAccess | |
dc.title | Regeneration of the peripheral nerve - Development and evaluation of guide tubes of biodegradable polymer | |
dc.type | Artigo em Livro de Atas de Conferência Internacional | |
dc.contributor.uporto | Faculdade de Engenharia | |
dc.identifier.doi | 10.1109/enbeng.2017.7889482 | |
dc.identifier.authenticus | P-00M-QWM | |
Appears in Collections: | FEUP - Artigo em Livro de Atas de Conferência Internacional |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
275520.pdf | 1.01 MB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.