Please use this identifier to cite or link to this item: https://hdl.handle.net/10216/119294
Full metadata record
DC FieldValueLanguage
dc.creatorGomes, J
dc.creatorSantos, JD
dc.creatorMauricio, AC
dc.date.accessioned2019-03-16T00:14:04Z-
dc.date.available2019-03-16T00:14:04Z-
dc.date.issued2017
dc.identifier.othersigarra:275520
dc.identifier.urihttps://hdl.handle.net/10216/119294-
dc.description.abstractDamage to peripheral nerve fibers results in axonal loss and demyelination followed by regeneration and remyelination under optimal conditions with the possibility of some functional recovery. The experimental challenge is to accelerate axonal regeneration to promote reinnervation and improve functional recovery after peripheral nerve injury. In the past few decades, different types of biological or artificial guide tubes have been developed to bridge the gap of a sectioned nerve, to limit the fibrosis process and to orient the regenerating fibers towards the distal stump. Chitosan is widely used for biomedical applications, including crosslinked with other materials. In this work, chitosan guide tubes were produced and implanted using the rat sciatic nerve animal model. Functional tests were performed as well as a mechanical and structural characterization of the guide tubes. (c) 2017 IEEE.
dc.language.isoeng
dc.relation.ispartof2017 IEEE 5th Portuguese Meeting on Bioengineering (ENBENG)
dc.rightsopenAccess
dc.titleRegeneration of the peripheral nerve - Development and evaluation of guide tubes of biodegradable polymer
dc.typeArtigo em Livro de Atas de Conferência Internacional
dc.contributor.uportoFaculdade de Engenharia
dc.identifier.doi10.1109/enbeng.2017.7889482
dc.identifier.authenticusP-00M-QWM
Appears in Collections:FEUP - Artigo em Livro de Atas de Conferência Internacional

Files in This Item:
File Description SizeFormat 
275520.pdf1.01 MBAdobe PDFThumbnail
View/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.