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https://hdl.handle.net/10216/114866
Author(s): | Leventakou, V Roumeliotaki, T Martinez, D Barros, H Brantsaeter, AL Casas, M Charles, MA Cordier, S Eggesbo, M van Eijsden, M Forastiere, F Gehring, U Govarts, E Halldorsson, TI Hanke, W Haugen, M Heppe, D Heude, B Inskip, HM Jaddoe, V Jansen, M Kelleher, C Meltzer, HM Merletii, F Moltó-Puigmartí, C Mommers, M Murcia, M Oliveira, A Olsen, SF Pele, F Polanska, K Porta, D Richiardi, L Robinson, SM Stigum, H|Strøm, M Sunyer, J Thijs, C Viljoen, K Vrijkotte, T Wijga, AH Kogevinas, M Vrijheid, M Chatzi, L |
Title: | Fish intake during pregnancy, fetal growth, and gestational length in 19 European birth cohort studies |
Issue Date: | 2014 |
Abstract: | BACKGROUND: Fish is a rich source of essential nutrients for fetal development, but in contrast, it is also a well-known route of exposure to environmental pollutants. OBJECTIVE: We assessed whether fish intake during pregnancy is associated with fetal growth and the length of gestation in a panel of European birth cohort studies. DESIGN: The study sample of 151,880 mother-child pairs was derived from 19 population-based European birth cohort studies. Individual data from cohorts were pooled and harmonized. Adjusted cohort-specific effect estimates were combined by using a random- and fixed-effects meta-analysis. RESULTS: Women who ate fish >1 time/wk during pregnancy had lower risk of preterm birth than did women who rarely ate fish (≤ 1 time/wk); the adjusted RR of fish intake >1 but <3 times/wk was 0.87 (95% CI: 0.82, 0.92), and for intake ≥ 3 times/wk, the adjusted RR was 0.89 (95% CI: 0.84, 0.96). Women with a higher intake of fish during pregnancy gave birth to neonates with a higher birth weight by 8.9 g (95% CI: 3.3, 14.6 g) for >1 but <3 times/wk and 15.2 g (95% CI: 8.9, 21.5 g) for ≥ 3 times/wk independent of gestational age. The association was greater in smokers and in overweight or obese women. Findings were consistent across cohorts. CONCLUSION: This large, international study indicates that moderate fish intake during pregnancy is associated with lower risk of preterm birth and a small but significant increase in birth weight. |
Subject: | Fish intake Pregnancy Fetal growth |
URI: | http://hdl.handle.net/10216/114866 |
Source: | Am J Clin Nutr, vol. 9(3), p. 506-516 |
Document Type: | Artigo em Revista Científica Internacional |
Rights: | openAccess |
Appears in Collections: | ISPUP - Artigo em Revista Científica Internacional |
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File | Description | Size | Format | |
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LeventakouVRoumeliotakeT2014.pdf | 263.97 kB | Adobe PDF | View/Open |
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