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https://hdl.handle.net/10216/111802
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DC Field | Value | Language |
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dc.creator | Draper, ES | - |
dc.creator | Manktelow, BN | - |
dc.creator | Cuttini, M | - |
dc.creator | Maier, RF | - |
dc.creator | Fenton, AC | - |
dc.creator | Van Reempts, P | - |
dc.creator | Bonamy, AK | - |
dc.creator | Mazela, J | - |
dc.creator | Bᴓrch, K | - |
dc.creator | Koopman-Esseboom, C | - |
dc.creator | Varendi, H | - |
dc.creator | Barros, H | - |
dc.creator | Zeitlin, JJ | - |
dc.date.accessioned | 2018-05-02T15:10:24Z | - |
dc.date.available | 2018-05-02T15:10:24Z | - |
dc.date.issued | 2017 | - |
dc.identifier.issn | 1098-4275 | - |
dc.identifier.uri | http://hdl.handle.net/10216/111802 | - |
dc.description.abstract | BACKGROUND AND OBJECTIVE: Stillbirth and in-hospital mortality rates associated with very preterm births (VPT) vary widely across Europe. International comparisons are complicated by a lack of standardized data collection and differences in definitions, registration, and reporting. This study aims to determine what proportion of the variation in stillbirth and in-hospital VPT mortality rates persists after adjusting for population demographics, case-mix, and timing of death. METHODS: Standardized data collection for a geographically defined prospective cohort of VPTs (22+0–31+6 weeks gestation) across 16 regions in Europe. Crude and adjusted stillbirth and in-hospital mortality rates for VPT infants were calculated by time of death by using multinomial logistic regression models. RESULTS: The stillbirth and in-hospital mortality rate for VPTs was 27.7% (range, 19.9%–35.9% by region). Adjusting for maternal and pregnancy characteristics had little impact on the variation. The addition of infant characteristics reduced the variation of mortality rates by approximately one-fifth (4.8% to 3.9%). The SD for deaths <12 hours after birth was reduced by one-quarter, but did not change after risk adjustment for deaths ≥12 hours after birth. CONCLUSIONS: In terms of the regional variation in overall VPT mortality, over four-fifths of the variation could not be accounted for by maternal, pregnancy, and infant characteristics. Investigation of the timing of death showed that these characteristics only accounted for a small proportion of the variation in VPT deaths. These findings suggest that there may be an inequity in the quality of care provision and treatment of VPT infants across Europe. | pt_PT |
dc.language.iso | eng | pt_PT |
dc.publisher | American Academy of Pediatrics | pt_PT |
dc.relation.ispartofseries | Pediatrics, vol. 139(4), p. e20161990 | pt_PT |
dc.rights | openAccess | pt_PT |
dc.subject | Stillbirth | pt_PT |
dc.title | Variability in Very Preterm Stillbirth and In-Hospital Mortality Across Europe | pt_PT |
dc.type | Artigo em Revista Científica Internacional | pt_PT |
dc.contributor.uporto | Instituto de Saúde Pública | pt_PT |
dc.identifier.doi | 10.1542/peds.2016-1990 | - |
dc.relation.publisherversion | http://pediatrics.aappublications.org/content/139/4/e20161990 | - |
Appears in Collections: | ISPUP - Artigo em Revista Científica Internacional |
Files in This Item:
File | Description | Size | Format | |
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Draper1394.pdf | 1.18 MB | Adobe PDF | View/Open |
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