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dc.creatorCerny, V-
dc.creatorMulligan, CJ-
dc.creatorFernandes, V-
dc.creatorSilva, NM-
dc.creatorAlshamali, F-
dc.creatorNon, A-
dc.creatorHarich, N-
dc.creatorCherni, L-
dc.creatorEl Gaaied, ABA-
dc.creatorAl-Meeri, A-
dc.creatorPereira, L-
dc.description.abstractWidespread interest in the first successful Out of Africa dispersal of modern humans ∼60-80 thousand years ago via a southern migration route has overshadowed the study of later periods of South Arabian prehistory. In this work, we show that the post-Last Glacial Maximum period of the past 20,000 years, during which climatic conditions were becoming more hospitable, has been a significant time in the formation of the extant genetic composition and population structure of this region. This conclusion is supported by the internal diversification displayed in the highly resolved phylogenetic tree of 89 whole mitochondrial genomes (71 being newly presented here) for haplogroup R0a-the most frequent and widespread haplogroup in Arabia. Additionally, two geographically specific clades (R0a1a1a and R0a2f1) have been identified in non-Arabic speaking peoples such as the Soqotri and Mahri living in the southern part of the Arabian Peninsula where a past refugium was identified by independent archaeological studies. Estimates of time to the most recent common ancestor of these lineages match the earliest archaeological evidence for seafaring activity in the peninsula in the sixth millennium BC.-
dc.description.sponsorshipThis project was supported by the Fulbright-Masaryk Fellowship of V.C. at the Department of Anthropology, University of Florida, the Ministry of Education of the Czech Republic, Grant number: KONTAKT ME 917, the Council of American Overseas Research Centers, the American Institute for Yemeni Studies, and the Portuguese Fundação para a Ciência e a Tecnologia (PTDC/ANT/66275/2006) (L.P.), (Instituto de Patologia e Imunologia Molecular da Universidade do Porto is an Associate Laboratory of the Portuguese Ministry of Science, Technology and Higher Education and is partially supported by the Portuguese Foundation for Science and Technology, FCT). This research was also supported by a grant from the National Science Foundation to C.J.M. (BSR-0518530).-
dc.publisherOxford University Press-
dc.relation.ispartofMolecular Biology and Evolution, vol. 28(1), p. 71-8-
dc.subjectSouth Arabia-
dc.subjectR0a haplogroup-
dc.titleInternal diversification of mitochondrial haplogroup R0a reveals post-Last Glacial Maximum demographic expansions in South Arabia-
dc.typeArtigo em Revista Científica Internacional-
dc.contributor.uportoInstituto de Investigação e Inovação em Saúde-
Appears in Collections:I3S - Artigo em Revista Científica Internacional

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