https://hdl.handle.net/10216/5397 Tue, 07 Apr 2026 11:39:55 GMT 2026-04-07T11:39:55Z https://hdl.handle.net/10216/172599 Title: Introdução da classificação da participação dos estudantes na avaliação da aprendizagem em Alimentação Humana Wed, 01 Jan 2025 00:00:00 GMT https://hdl.handle.net/10216/172599 2025-01-01T00:00:00Z https://hdl.handle.net/10216/173774 Title: Código de ética da Universidade do Porto = Code of ethics of the University of Porto Abstract: "The University of Porto (U.Porto), in line with its mission of education, creation, and dissemination of knowledge, science and art, is committed to a culture of quality and high standards, adopting recognised integrity and ethical standards suited to its functions and role in society. The principles of ethical conduct adopted by U.Porto aim to continuously improve its performance in all areas of operation. These principles apply to the entire academic community, including all members of governing bodies, teaching and research staff, students, scholarship holders, executive, technical, specialist and management staff, regardless of their professional status, attendance regime, or the nature of their ties and contracts with the institution. When financing, providing services to or collaborating in activities at U.Porto, external entities must be guided by the same ethical principles set forth in this Code." - Preamble Description: "A Universidade do Porto (U.Porto), na consecução dos seus fins de formação, criação e difusão de conhecimento, ciência e arte, está comprometida com uma cultura de qualidade e de exigência, assumindo padrões éticos e de integridade reconhecidos e adequados às suas funções e ao seu papel na sociedade. Os princípios de conduta ética adotados pela U.Porto visam a melhoria contínua da sua prestação em todos os domínios nos quais desenvolva atividade. Esses princípios dizem respeito a toda a comunidade académica, onde se incluem todos os membros dos órgãos de governo, o pessoal docente e investigador, os estudantes, os bolseiros, o pessoal dirigente e técnico, especialista e de gestão, independentemente do respetivo estatuto profissional, do regime de frequência, ou da natureza dos seus vínculos e contratos com a instituição. As entidades externas quando financiam, prestam serviços ou colaboram em atividades da U.Porto devem pautar-se pelos mesmos princípios éticos expressos neste Código." - Preâmbulo Wed, 01 Jan 2025 00:00:00 GMT https://hdl.handle.net/10216/173774 2025-01-01T00:00:00Z https://hdl.handle.net/10216/173764 Title: Food Consumption and Seasonality: the effect of local seasonal food on the sustainable consumption perception of different stakeholders Mon, 02 Mar 2026 00:00:00 GMT https://hdl.handle.net/10216/173764 2026-03-02T00:00:00Z https://hdl.handle.net/10216/173712 Title: Provas de Agregação Description: Lição síntese: "Adequação da adição de sal como um dos princípios da culinária saudável e sustentável" Thu, 12 Feb 2026 00:00:00 GMT https://hdl.handle.net/10216/173712 2026-02-12T00:00:00Z https://hdl.handle.net/10216/169488 Title: Provas de Agregação Description: Lição síntese: Perigos Microbiológicos na Cadeia Alimentar: Desafios na Era da Genómica e Uma Só Saúde. Mon, 07 Jul 2025 00:00:00 GMT https://hdl.handle.net/10216/169488 2025-07-07T00:00:00Z https://hdl.handle.net/10216/173634 Title: Manual de equivalentes alimentares orientado para o controlo de proteína, fósforo e potássio Editors: Franchini, Bela; Azevedo, Marta; Graça, Pedro Thu, 01 Jan 2026 00:00:00 GMT https://hdl.handle.net/10216/173634 2026-01-01T00:00:00Z https://hdl.handle.net/10216/173646 Title: Assessing the sustainability of dietary patterns in Portugal: A multidimensional approach based on environmental, nutritional, and economic dimensions Tue, 03 Mar 2026 00:00:00 GMT https://hdl.handle.net/10216/173646 2026-03-03T00:00:00Z https://hdl.handle.net/10216/156363 Title: Avaliação da oferta Alimentar em Bufetes de Escolas do 2.º Ciclo do Ensino Básico do Distrito de Faro Sun, 01 Jan 2023 00:00:00 GMT https://hdl.handle.net/10216/156363 2023-01-01T00:00:00Z https://hdl.handle.net/10216/173504 Title: Feasibility and Effectiveness of a Social Network-Based Intervention for Adolescents Undergoing Weight Loss Treatment: A Randomized Controlled Trial Abstract: Background/Objectives: Digital interventions can have a positive effect on the health-related behaviors of adolescents. However, it is unclear if social network-based interventions using Facebook can help to optimize medical treatment as usual (TAU) for adolescent obesity in public health care centers. We examined the feasibility, usability, and effectiveness of APOLO-Teens, a Cognitive Behavioral Therapy Facebook-based intervention as a supplement to TAU on changing eating habits/behaviors, physical activity levels, and psychological functioning of adolescents with overweight/obesity. Methods: This was a Randomized Controlled Trial (Trial registration number: NCT04642222). One-hundred and thirty-five adolescents aged 13 to 18 years (67.5% females) were randomly assigned to the TAU control group (n = 66) and the APOLO-Teens intervention group (n = 69). Intervention outcomes were measured at baseline and the end of the intervention (6 months later). Using per-protocol analysis, the sample size retained for final analysis included 77 participants (Control group = 39; Intervention group = 38). Two-way mixed ANOVAs were used to test within-and between-group changes. Results: The APOLO-Teens social network-based intervention was feasible (adherence rate: 85.5%) and the intervention group had a significant increase in fruit consumption (F (1,35) = 6.99, p = 0.012; significant group-by-time interaction). Both groups increased vegetables on the plate consumption and decreased pastries/cakes intake, depressive symptomatology, grazing eating pattern, and BMI z-score (p < 0.05; significant time interaction). Conclusions: The APOLO-Teens social network-based intervention was feasible, and the effectiveness results suggest that it can be a beneficial supplementary intervention to TAU in adolescent obesity. Wed, 01 Jan 2025 00:00:00 GMT https://hdl.handle.net/10216/173504 2025-01-01T00:00:00Z https://hdl.handle.net/10216/168448 Title: Insights towards the impact of subinhibitory chlorhexidine on antimicrobial susceptibility and horizontal gene transfer in Enterococcus faecium Abstract: Enterococcus faecium, a human and animal commensal broadly distributed in the environment, is currently one of the most challenging multidrug-resistant (MDR) healthcare-associated pathogens worldwide. It is often exposed to chlorhexidine (CHX), a broad-spectrum antiseptic, extensively used in healthcare, domestic, and food production settings, and a diffused polluter. However, the impact of gradients of CHX concentrations, including at subinhibitory levels, on E. faecium adaptation to various antimicrobials remains unclear. Our study aimed to explore the effects of subinhibitory CHX concentrations on biocides and antibiotics susceptibility as well as in the transfer of clinically relevant antibiotic resistance genes among E. faecium (n = 11) from diverse sources and clonal backgrounds. Serial exposure to increasing CHX concentrations resulted in strain-specific MICCHX and MBCCHX changes among six E. faecium studied. These strains presented different CHX genotypes, namely the P102H mutation in DNA-binding response regulator ChtR in two strains showing twofold increased MICCHX and/or MBCCHX, and an absent EfrEF transporter in a strain exhibiting increased CHX susceptibility after exposure. Whole-genome comparison between parental and CHX-adapted strains found no alterations in genes with a recognized role in CHX reduced susceptibility. Additionally, in a different assay, subinhibitory CHX exposure enhanced the transfer (up to 12.5-fold) of vancomycin or linezolid resistance genes among most E. faecium strains tested, except one lacking a functional EfrEF transporter. Our data suggest that subinhibitory CHX concentrations could have a role in Enterococcus adaptation to CHX and in the spread of antibiotic resistance through horizontal transfer events. Further investigation is warranted to elucidate the underlying mechanisms driving these phenomena in E. faecium, ensuring the continued effectiveness of both CHX and antibiotics, and safeguarding Public Health. (c) 2025 The Authors Wed, 01 Jan 2025 00:00:00 GMT https://hdl.handle.net/10216/168448 2025-01-01T00:00:00Z https://hdl.handle.net/10216/172078 Title: Trihydroxylated Anthocyanins Potentiate Effects of Docetaxel in Mesenchymal Triple Negative Breast Cancer Cells Abstract: Triple negative breast cancer (TNBC) presents a significant therapeutic challenge due to its poor prognosis and limited treatment options. While anthocyanins, a group of flavonoids, exhibit promising anticancer potential, their structureactivity relationship and adjuvant properties in TNBC remain underexplored. This study evaluated the anti-proliferative effects of five structurally distinct anthocyani(di)nscyanidin-3-O-glucoside (C3G), delphinidin-3-O-glucoside (D3G), delphinidin-3-O-rutinoside (D3R), malvidin-3-O-glucoside (M3G), and luteolinidin (LT)on mesenchymal TNBC cells. Combination assays of docetaxel (DT), a first-line chemotherapeutic agent, with the most potent anthocyani(di)ns were conducted with TNBC and MCF-12A non-cancerous cells. Trihydroxylated anthocyanins (D3G and D3R), particularly those with a monosaccharide at C3, demonstrated the strongest anti-proliferative effects, reducing MDA-MB-231 cell proliferation by 95% and 70%, respectively, at 400 M (IC<inf>50</inf>: 253.28 and 341.33 M) without affecting MCF-12A cells. These were followed by 3-deoxy (LT), dihydroxylated (C3G), and O-methylated (M3G) anthocyani(di)ns. In Hs 578T mesenchymal TNBC cells, the trihydroxylated anthocyanins tested also induced strong anti-proliferative effects. Synergistic effects (combination index < 0.9) were observed for binary (D3G + DT or D3R + DT) and ternary (D3G + D3R + DT) combinations, reducing DT concentrations by up to 37-fold and anthocyanin concentrations by up to 21.9-fold to achieve similar inhibition. The ternary combination was the most effective, requiring the lowest concentrations of DT and anthocyanins. These results underscore the critical role of the ortho-trihydroxylated structure in the anti-proliferative effects of anthocyani(di)ns, highlighting trihydroxylated anthocyanins as promising adjuvants in TNBC treatment, with the potential to lower DT dosage, minimize side effects, delay resistance, and reduce treatment costs while maintaining efficacy. (c) 2025 The Author(s). BioFactors published by Wiley Periodicals LLC on behalf of International Union of Biochemistry and Molecular Biology. Wed, 01 Jan 2025 00:00:00 GMT https://hdl.handle.net/10216/172078 2025-01-01T00:00:00Z https://hdl.handle.net/10216/172956 Title: Psychological aspects of grazing in adolescents: psychometric properties and measurement invariance of the Rep(eat)‑Q in community and clinical samples Wed, 01 Jan 2025 00:00:00 GMT https://hdl.handle.net/10216/172956 2025-01-01T00:00:00Z https://hdl.handle.net/10216/151207 Title: Accuracy of Assessing Weight Status in Adults by Structured Observation Abstract: <jats:p>The assessment of weight status is important in many epidemiological studies, but its direct measurement is not always possible. Self-reported weight and height are often used, although previous research reported low accuracy. This study aimed to test the ability of trained observers to accurately estimate weight status in adults using structured observation. A cross-sectional study was conducted. For each participant, height and weight were estimated in categories, and weight status was recorded using Stunkards body figures, by two trained observers. Height and weight were also measured, using standardized procedures. Subjects were classified according to World Health Organization body mass index (BMI) cut-offs from objective measurements and from the BMI assigned to each body figure. Sensitivity, specificity, and likelihood ratios were calculated to assess the accuracy of estimating weight status by observation. Kappa was used to test inter-observer reliability. A total of 127 participants were assessed, 70 women and 57 men, aged between 19 and 89 years (mean ± standard deviation: 50.3 ± 16.3 years). Most participants were overweight or obese (64.3% women; 78.9% men). The sensitivity and specificity of overweight/obesity status identification were 72.8% and 78.4%, respectively. Observers gender, participants gender, and participants age were significantly associated with the estimation of overweight/obesity. The agreement between observers was moderate for BMI estimates ( = 0.52) but substantial when distinguishing normal weight from overweight/obesity ( = 0.67). Trained observers were able to distinguish normal weight from overweight/obesity with high sensitivity and specificity, and substantial interrater reliability. This innovative methodology showed potential for improvement through enhanced training techniques. The use of structured observation may be a useful and accurate alternative to self-reported weight status assessment, whenever anthropometric measurement is not achievable.</jats:p> Sun, 01 Jan 2023 00:00:00 GMT https://hdl.handle.net/10216/151207 2023-01-01T00:00:00Z https://hdl.handle.net/10216/172868 Title: Impact of subinhibitory concentrations of chlorhexidine on in vitro horizontal transfer of vancomycin and linezolid resistance genes in Enterococcus faecium. Mon, 01 Jan 2024 00:00:00 GMT https://hdl.handle.net/10216/172868 2024-01-01T00:00:00Z https://hdl.handle.net/10216/172864 Title: A dive into diversity and antimicrobial resistance of Enterococcus from rivers used for drinking water production Mon, 01 Jan 2024 00:00:00 GMT https://hdl.handle.net/10216/172864 2024-01-01T00:00:00Z https://hdl.handle.net/10216/172861 Title: Exploring tolerance to quaternary ammonium compounds in Klebsiella pneumoniae with a focus on the food chain: phenotypic and genomic insights Mon, 01 Jan 2024 00:00:00 GMT https://hdl.handle.net/10216/172861 2024-01-01T00:00:00Z https://hdl.handle.net/10216/118069 Title: Street food in Maputo, Mozambique: Availability and nutritional value of homemade foods Abstract: Background: A nutrition transition is occurring in the urban areas of developing countries, where street food makes an important contribution to daily food intake. Aim: We aimed to characterise street food offer in Maputo, Mozambique, and to evaluate the nutritional composition of the most common homemade foods. Methods: A cross-sectional study was conducted in 2014. Streets in the surroundings (500 m buffer) of randomly selected public transport stops in KaMpfumu district, Maputo, were canvassed to identify all street food vending sites (n = 968). Information regarding vending site characteristics and the food offered was gathered through interview and observation. Samples (n = 80) of the most common homemade foods were collected for laboratorial analysis. Results: Most street food vending sites identified were stationary (77.4%) and sold exclusively industrial food (51.9%). Frequency of fruit, beverages and food other than fruit was 24.5%, 32.5% and 73.9%, respectively. Fried cakes were the most energy-dense (430 kcal/100 g), and richest in fats (21.0g/100 g) and carbohydrates (53.4 g/100 g). The richest sources of protein were the stewed meat/fish/liver dishes (10.711.6 g/100 g). Fried cakes showed the lowest sodium and potassium content (90 mg/100 g and 81 mg/100 g, respectively) whereas hamburgers exhibited the highest content of those micronutrients (455 mg/100 g and 183 mg/100 g, respectively). Stewed liver dishes presented the highest sodium/potassium ratio (11.95). Fried snacks presented the highest trans-fatty acid content (0.20 g/100 g). Conclusions: Street food in Maputo is abundant and scattered throughout the urban district, exhibiting high variability in the nutritional composition of homemade foods. Public health policies should be targeted to improve the street food offer, promoting nutrient-dense foods and the reduction of added salt. (c) The Author(s) 2018. Mon, 01 Jan 2018 00:00:00 GMT https://hdl.handle.net/10216/118069 2018-01-01T00:00:00Z https://hdl.handle.net/10216/151371 Title: Methodological approaches for the assessment of bisphenol A exposure Sun, 01 Jan 2023 00:00:00 GMT https://hdl.handle.net/10216/151371 2023-01-01T00:00:00Z https://hdl.handle.net/10216/130167 Title: Street food in Eastern Europe: a perspective from an urban environment in Moldova Abstract: Street food is popular in Eastern Europe, but its diversity and nutritional value are unknown. This study aimed to characterise the street food environment in Chisinau, Moldova, including the vending sites and vendors, food availability and nutritional composition of foods and beverages. All street food vending sites (single point of sale) located in a 1-km buffer centred on the main public market were systematically selected (n439;n328 participants). Data on vending sites' characteristics (mobility, type of physical set-up and access to electricity), operating periods and food availability were collected. Samples of the most commonly available foods of unknown composition were collected (twenty-eight home-made and twenty-four industrial). Macronutrients, Na and K were quantified through chemical analysis. Fruits, beverages and food other than fruits were available in 2 center dot 5, 74 center dot 3 and 80 center dot 8 % of the vending sites, respectively. Among the latter, 66 center dot 4 % sold only industrial foods (e.g. pretzels, biscuits, wafers, chocolate and ice cream), 21 center dot 5 % only home-made (e.g. savoury and sweet pastries) and 12 center dot 1 % both. Home-made foods presented larger serving sizes and energy/serving (median kJ/serving: 1312 center dot 5v.670 center dot 3,P= 0 center dot 022); industrial foods were more energy-dense (median kJ/100 g: 1797 center dot 0v.1269 center dot 8,P= 0 center dot 002). High SFA,trans-fat and Na contents were found, reaching 10 center dot 9 g/serving, 1 center dot 4 g/serving and 773 center dot 7 mg/serving, respectively. Soft drinks and alcoholic beverages were available in 80 center dot 7 and 42 center dot 0 % of the vending sites selling beverages, respectively. Concluding, industrial snacks and home-made pastries high in Na and unhealthy fat were frequent in Chisinau. Prevention of diet-related diseases in Moldova may benefit from the improvement of the nutritional profile of street food. Wed, 01 Jan 2020 00:00:00 GMT https://hdl.handle.net/10216/130167 2020-01-01T00:00:00Z https://hdl.handle.net/10216/168458 Title: Iodine supplementation for pregnancy in Portugal: identification of nutritional composition of iodine containing supplements and characterization of pharmacy dispenses from 2008-2022 Abstract: Background Iodine is essential for the proper development of the central nervous system. In Portugal, despite of self-reports of iodine supplements intake by pregnant women, iodine deficiency still prevails. This study intended to characterize the pharmacy sales of iodine-containing supplements and their use by women in Portugal.Methods Data from all available supplements with indication for use in the prenatal time, for the period 2008-2022, was obtained from the Portuguese Association of Pharmacies. To infer from the use of iodine supplements by women during preconception, pregnancy and lactation, pharmacy dispenses, between 2019 and 2021, were collected from a sample of female consumers, identified with at least one prescription of iodine-containing supplements.Results Eighty-eight per cent of the iodine-containing supplements state the recommended iodine concentration. The annual sales increased continuously, reaching an estimated of 109 mu g per day in 2022. Estimated mean duration of supplementation to women prescribed with iodine-containing supplements for preconception/pregnancy/lactation was of 4.5 months (SD = 3.8) and less than 1% of women was covered for the advisable period of 18 months.Conclusion The estimated duration of iodine supplementation to women during preconception, pregnancy and lactation is below recommendations. Additional public health measures, such as universal salt iodization and literacy campaigns are needed to ensure iodine sufficiency to women and their developing fetus. Wed, 01 Jan 2025 00:00:00 GMT https://hdl.handle.net/10216/168458 2025-01-01T00:00:00Z