https://hdl.handle.net/10216/26777 Fri, 10 Jul 2026 14:59:32 GMT 2026-07-10T14:59:32Z https://hdl.handle.net/10216/172964 Title: Aprendizagem colaborativa e responsabilidade social das universidades na prevenção do consumo de novas substâncias psicoativas Wed, 01 Jan 2025 00:00:00 GMT https://hdl.handle.net/10216/172964 2025-01-01T00:00:00Z https://hdl.handle.net/10216/172959 Title: O papel do feedback dos estudantes na avaliação e inovação curricular: uma experiência em ciências farmacêuticas Wed, 01 Jan 2025 00:00:00 GMT https://hdl.handle.net/10216/172959 2025-01-01T00:00:00Z https://hdl.handle.net/10216/172079 Title: Hygiene challenges in foodservice units: biocide efficacy and bacterial diversity across surfaces Wed, 01 Jan 2025 00:00:00 GMT https://hdl.handle.net/10216/172079 2025-01-01T00:00:00Z https://hdl.handle.net/10216/165724 Title: A educação em ciências da saúde e a responsabilidade social das universidades Mon, 01 Jan 2024 00:00:00 GMT https://hdl.handle.net/10216/165724 2024-01-01T00:00:00Z https://hdl.handle.net/10216/165714 Title: Integração na profissão: o primeiro passo na formação em ciências farmacêuticas Mon, 01 Jan 2024 00:00:00 GMT https://hdl.handle.net/10216/165714 2024-01-01T00:00:00Z https://hdl.handle.net/10216/165395 Title: Integração e vivências solidárias no ensino superior: contributos de programas de mentoria interpares Mon, 01 Jan 2024 00:00:00 GMT https://hdl.handle.net/10216/165395 2024-01-01T00:00:00Z https://hdl.handle.net/10216/162483 Title: Integrating Metacognition in Physiology Education Tue, 14 Nov 2023 00:00:00 GMT https://hdl.handle.net/10216/162483 2023-11-14T00:00:00Z https://hdl.handle.net/10216/165066 Title: Mentoria Profissional na FFUP estratégia facilitadora da transição para o mercado de trabalho e de redução do abandono académico Sat, 01 Jul 2023 00:00:00 GMT https://hdl.handle.net/10216/165066 2023-07-01T00:00:00Z https://hdl.handle.net/10216/165062 Title: Explorando o "Circuito do Medicamento" como uma estratégia interativa de integração académica para os estudantes do 1º ano de Ciências Farmacêuticas Mon, 01 Jan 2024 00:00:00 GMT https://hdl.handle.net/10216/165062 2024-01-01T00:00:00Z https://hdl.handle.net/10216/164682 Title: Indicadores de higiene e biocidas em superfícies do ambiente de preparação e distribuição de alimentos em unidades de restauração coletiva Mon, 01 Jan 2024 00:00:00 GMT https://hdl.handle.net/10216/164682 2024-01-01T00:00:00Z https://hdl.handle.net/10216/163817 Title: Persistence of mcr-1 carrying Escherichia coli after colistin ban in rabbit farms: implications for One-Health strategies Mon, 01 Jan 2024 00:00:00 GMT https://hdl.handle.net/10216/163817 2024-01-01T00:00:00Z https://hdl.handle.net/10216/162147 Title: Bioprospection of antibiotics and biofilm inhibitors from under-exploited filamentous fungi Abstract: In the past century, antibiotics revolutionized the way infectious diseases were treated, saving millions of lives. However, bacteria, in particular these infectious, may develop antibiotic resistance in such a way that the speed of development of new drugs does not follows the development of resistance. Filamentous fungi have a vast, largely unexplored metabolome, giving them great potential for novel antibiotic discovery. The One Strain MAny Compounds (OSMAC) approach is a valuable tool in this regard and aims to vary culture conditions to obtain a wider range of metabolites. In this study, five under-explored fungal species were used, aiming to identify compounds with antibiotic or antibiofilm properties produced by them. They were grown in different culture media, under deep fermentation for 7 and 14 days, with changing conditions of aeration and agitation, and the resulting supernatants were tested for their antimicrobial activity against Gram-positive and Gram-negative bacteria using the disk diffusion method. All fungi grew on the different media and under the diverse process conditions. It was found that Coprinopsis spilospora metabolites inhibited Staphylococcus aureus growth and demonstrated antibiofilm properties. They reduced the biofilm in 30% in crystal violet staining, metabolic activity by 82% in Alamar blue test, and viable cells counts by 96% in CFU counting. Co-culture and disk diffusion test results also showed that this supernatant has a slight effect against Escherichia coli. The pioneer results obtained in the present study highlight the relevance of bioprospection for antibiotic discovery. Fri, 12 May 2023 00:00:00 GMT https://hdl.handle.net/10216/162147 2023-05-12T00:00:00Z https://hdl.handle.net/10216/159061 Title: Invisible dangers on our plates: a critical review of the widespread presence of microplastics and nanoplastics in food Mon, 01 Jan 2024 00:00:00 GMT https://hdl.handle.net/10216/159061 2024-01-01T00:00:00Z https://hdl.handle.net/10216/159053 Title: Assessment of antimicrobial resistance in Gram-negative bacteria from rivers supplying drinking water: insights for water quality management Mon, 01 Jan 2024 00:00:00 GMT https://hdl.handle.net/10216/159053 2024-01-01T00:00:00Z https://hdl.handle.net/10216/159052 Title: A dive into diversity and antimicrobial resistance of Enterococcus from rivers used for drinking water production Mon, 01 Jan 2024 00:00:00 GMT https://hdl.handle.net/10216/159052 2024-01-01T00:00:00Z https://hdl.handle.net/10216/159044 Title: Optimization of DNA Extraction Methods for Metagenomic Analysis in Surface Water Samples Mon, 01 Jan 2024 00:00:00 GMT https://hdl.handle.net/10216/159044 2024-01-01T00:00:00Z https://hdl.handle.net/10216/156134 Title: Genomic Diversity of Klebsiella pneumoniae in Chicken Production Chain: Antibiotic Resistance and Metal Tolerance Interplay Sun, 01 Jan 2023 00:00:00 GMT https://hdl.handle.net/10216/156134 2023-01-01T00:00:00Z https://hdl.handle.net/10216/156133 Title: Uncovering Seasonal Variations in Antimicrobial-Resistant Enterococcus Diversity within Porto Region's Surface Waters Sun, 01 Jan 2023 00:00:00 GMT https://hdl.handle.net/10216/156133 2023-01-01T00:00:00Z https://hdl.handle.net/10216/156132 Title: Long-term persistence of mcr-1 carrying Escherichia coli in intensive rabbit farms after colistin ban Sun, 01 Jan 2023 00:00:00 GMT https://hdl.handle.net/10216/156132 2023-01-01T00:00:00Z https://hdl.handle.net/10216/156131 Title: Assessing Gram-Negative Antimicrobial Resistant Bacteria in Rivers for Drinking Water: A Seasonal Analysis Sun, 01 Jan 2023 00:00:00 GMT https://hdl.handle.net/10216/156131 2023-01-01T00:00:00Z