https://hdl.handle.net/10216/5644 2026-07-10T14:55:04Z https://hdl.handle.net/10216/169528 Title: Effect of Denture Adhesives on the Surface Roughness and Hardness of Denture Base Resins - A Preliminary Study 2025-01-01T00:00:00Z https://hdl.handle.net/10216/174328 Title: AI based rehabilitation: the way forward in addressing unmet needs in musculoskeletal disease 2026-01-01T00:00:00Z https://hdl.handle.net/10216/174271 Title: From Alginate to Pixel: Comparing the Effect of Two Dental Impression Methods on Children's Anxiety 2025-01-01T00:00:00Z https://hdl.handle.net/10216/166769 Title: Achieving patency in straight canals obturated with Ah Plus Bioceramic sealer: An Ex Vivo Study 2025-01-01T00:00:00Z https://hdl.handle.net/10216/173776 Title: Oral healthcare in maternal health services: a cross-country comparative analysis in 10 European countries 2026-01-01T00:00:00Z https://hdl.handle.net/10216/172272 Title: Botulinum Toxin Effects on Biochemical Biomarkers Related to Inflammation-Associated Head and Neck Chronic Conditions: A Systematic Review of Preclinical Research 2025-01-01T00:00:00Z https://hdl.handle.net/10216/172167 Title: The Graduating European Dentist Curriculum Framework:A Multi-Stakeholder View 2025-01-01T00:00:00Z https://hdl.handle.net/10216/172154 Title: Botulinum toxin effects on biochemical biomarkers related to inflammation-associated head and neck chronic conditions: a systematic review of clinical research 2025-01-01T00:00:00Z https://hdl.handle.net/10216/172102 Title: Exploring Additive Manufacturing for Sports Mouthguards: A Pilot Study 2026-01-01T00:00:00Z https://hdl.handle.net/10216/172087 Title: In Vitro Evaluation of the Antimicrobial Properties of Chitosan - Vancomycin Coatings on Grade 4 Titanium Discs: A Preliminary Study 2026-01-01T00:00:00Z https://hdl.handle.net/10216/157212 Title: Maxillary Sinus Augmentation with Xenogenic Collagen-Retained Heterologous Cortico-Cancellous Bone: A 3-Year Follow-Up Randomized Controlled Trial 2024-01-01T00:00:00Z https://hdl.handle.net/10216/170852 Title: Evidence-based position paper on Physical and Rehabilitation Medicine (PRM) professional practice on telerehabilitation. The European PRM position (UEMS PRM Section) 2024-01-01T00:00:00Z https://hdl.handle.net/10216/165212 Title: Importance of good hosting: reviewing the bi-directionality of the microbiome-gut-brain-axis 2024-01-01T00:00:00Z https://hdl.handle.net/10216/170120 Title: Pressing Issues for Oral Health Care Access and Quality Improvement During Pregnancyin Portugal - A Qualitative Study 2025-01-01T00:00:00Z https://hdl.handle.net/10216/169830 Title: Oral health practices and determinants among university students - A cross-sectional study = Práticas e determinantes de saúde oral entre estudantes universitários - um estudo transversal 2025-01-01T00:00:00Z https://hdl.handle.net/10216/167043 Title: Comparison of Modulation-Assisted Machining Strategies for Achieving Chip Breakage When Turning 17-4 PH Stainless Steel 2024-01-01T00:00:00Z https://hdl.handle.net/10216/162689 Title: Bone regeneration driven by a nano-hydroxyapatite/chitosan composite bioaerogel for periodontal regeneration Abstract: The most recent progress in reconstructive therapy for the management of periodontitis and peri-implantitis bone defects has relied on the development of highly porous biodegradable bioaerogels for guided bone regeneration. The objective of this work was to evaluate in vitro the osteoinduction of periodontal-originating cells (human dental follicle mesenchymal cells, DFMSCs) promoted by a nano-hydroxyapatite/chitosan (nHAp/CS) bioaerogel, which was purified and sterilized by a sustainable technique (supercritical CO2). Moreover, the in vivo bone regeneration capacity of the nHAp/CS bioaerogel was preliminarily assessed as a proof-of-concept on a rat calvaria bone defect model. The quantification of DNA content of DFMSCs seeded upon nHAp/CS and CS scaffolds (control material) showed a significant increase from the 14th to the 21st day of culture. These results were corroborated through confocal laser scanning microscopy analysis (CLSM). Furthermore, the alkaline phosphatase (ALP) activity increased significantly on the 21st day, similarly for both materials. Moreover, the presence of nHAp promoted a significantly higher expression of osteogenic genes after 21 days when compared to CS scaffolds and control. CLSM images of 21 days of culture also showed an increased deposition of OPN over the nHAp/CS surface. The in vivo bone formation was assessed by microCT and histological analysis. The in vivo evaluation showed a significant increase in bone volume in the nHAp/CS test group when compared to CS and the empty control, as well as higher new bone formation and calcium deposition within the nHAp/CS structure. Overall, the present study showed that the nHAp/CS bioaerogel could offer a potential solution for periodontal and peri-implant bone regeneration treatments since the in vitro results demonstrated that it provided favorable conditions for DFMSC proliferation and osteogenic differentiation, while the in vivo outcomes confirmed that it promoted higher bone ingrowth. 2024-01-01T00:00:00Z https://hdl.handle.net/10216/165634 Title: Nanostructured ZnO thin film to enhance gutta-percha's adhesion to endodontic sealers 2024-01-01T00:00:00Z https://hdl.handle.net/10216/165630 Title: Direct vs. Indirect Digital Implant Impressions: A Time and Cost Analysis 2024-01-01T00:00:00Z https://hdl.handle.net/10216/165624 Title: Chitosan's Ability to Remove the Smear Layer-A Systematic Review of Ex Vivo Studies 2025-01-01T00:00:00Z